Flea Free Ectoline duo dog 10-20kg pipette

Flea Free Ectoline duo dog 10-20kg pipette
RVG NL 116240 AV

FLEA FREE COMBO M, 134 mg/40 mg spot-on solution for medium dogs 10-20 kg
To be used for flea infestations alone or in conjunction with tick infestations.

Against fleas:
Treatment and prevention of flea infestations (Ctenocephalides felis). One treatment
prevents further infestations for 7 weeks.
Prevention of flea multiplication by preventing the development
of adult fleas from flea eggs for 12 weeks after administration.

Against ticks:
Treatment of tick infestations (Ixodes ricinus).
One treatment provides sustained acaricide effectiveness against Ixodes ricinus for 2
weeks and against Dermacentor reticulatus and Rhipicephalus sanguineus for 4 weeks.
If some species of ticks (Dermacentor reticulatus, Rhipicephalus sanguineus) are present
administration of the veterinary medicine is already present, it may be that not all ticks are within the
the first 48 hours are killed.

What is this product used for
To be used for flea infestations alone or in conjunction with tick infestations.

Do not use in
Do not use in rabbits, as side effects and even death may occur.
Do not use in known hypersensitivity to the active ingredients or any of the excipients.

Extra caution with
Special warnings for each animal species for which the veterinary medicinal product is intended
Washing with shampoo or immersing the animal in water immediately after treatment may reduce the duration of action. The veterinary medicinal product remains effective against fleas for 5 weeks if the dog is washed monthly with shampoo after treatment. If the dog needs to be washed, it is better to do this before treatment.
Immersion in water, repeated at two points after treatment, had no effect on the adulticidal activity against fleas, nor on the effectiveness related to the prevention of the development of adult fleas from flea eggs.
The effect of immersion in water or washing the dog with shampoo on the effectiveness of the veterinary medicinal product against ticks has not been evaluated.
At the beginning of control measures, in the case of an infestation, the dog bed, bedding, and regularly used resting places such as rugs and upholstery should be treated with an appropriate insecticide and vacuumed regularly.
To reduce flea infestation in the environment, all animals in the household should be treated with an appropriate flea control product.
The veterinary medicinal product does not prevent the attachment of ticks to the animals. Transmission of infectious diseases by ticks cannot be completely excluded if conditions are unfavorable. Immediate efficacy has been demonstrated against Ixodes ricinus, indicating that ticks of this species are likely to be killed within 48 hours after administration of the veterinary medicinal product.

If Dermacentor reticulatus or Rhipicephalus sanguineus ticks are present when the veterinary medicinal product is applied, these ticks may not be killed within the first 48 hours. Once the ticks are dead, they will usually fall off the animal. Remaining ticks should be removed carefully, ensuring that no mouthparts of the tick remain in the skin.

Intake during pregnancy and breastfeeding
Use during pregnancy, lactation, or laying
No data have emerged from laboratory studies with fipronil and pyriproxyfen
came forward indicating teratogenic or embryotoxic effects. The safety of this
veterinary medicinal product has not been demonstrated in pregnant and nursing bitches. Use during pregnancy and
lactation only in accordance with the benefit/risk assessment of the attending veterinarian.

Additional information
Special precautions for use in animals
For external use only.
Animals should be accurately weighed before treatment.
In the absence of safety data, the veterinary medicinal product should not be used in
puppies younger than 10 weeks and/or weighing less than 2 kg.
It is important to ensure that the contents of the pipette do not come into contact with the eyes or mouth.
of the dogs to be treated is avoided. In particular, oral intake due to licking
to the application site by treated animals or animals that have contact with treated
animals should be avoided.
Do not use the veterinary medicinal product on wounds or damaged skin.
In the absence of additional safety studies, the treatment should not be repeated.
to be administered at intervals of less than 4 weeks.
The use of the veterinary medicinal product has not been studied in sick and weakened animals.
Special precautions should be taken by the person administering the veterinary medicinal product to the
administers to animals
The veterinary medicinal product may cause neurotoxicity.
The veterinary medicinal product may be harmful if swallowed.
Prevent ingestion, including hand-mouth contact.

Do not smoke, drink, or eat during application.
In case of accidental ingestion, a doctor should be consulted immediately and the package leaflet
or the label to be displayed.
This veterinary medicine may cause irritation to eyes and mucous membranes.
Avoid contact with skin, eyes, and mouth, including hand-eye contact.
In case of accidental skin or eye contact, rinse thoroughly with water immediately.
If skin or eye irritation persists, a doctor should be consulted and the package leaflet or the
label to be displayed.
Wash hands after use.
Treated animals should not be touched until the application site is dry. Children should
not to play with the treated animals until the application site is dry. Therefore, it is recommended
to treat animals during the day but in the early evening and not to allow recently treated animals
to let sleep with the owners, especially children.
Keep the pipettes in the original packaging until the time of use and discard used
dispose of pipettes immediately.
Other precautions
Fipronil and pyriproxyfen may have harmful effects on aquatic organisms.
Dogs should not swim in open water for 48 hours after treatment (see also
section 6.6).
The veterinary medicine may have adverse effects on painted, varnished, or other
household surfaces or furniture. Allow the application site to dry before contact
occurs with such materials.

Overdose (symptoms, emergency procedures, antidotes), if necessary
No serious side effects were observed in a safety study with 10-week-old
puppies, which were treated three times with an interval of 4 weeks, with up to five times the maximum recommended dose and those treated six times with the maximum recommended dose with an interval of 4 weeks.
The risk of side effects occurring (see section 4.6) may increase with overdose, so animals must always be treated with the correct pipette size corresponding to their body weight.

Active ingredients
Active ingredients 1.34 ml pipette:
Fipronil 134.0 mg
Pyriproxyfen 40.2 mg

Excipients
Butylhydroxyanisole E320
Butylhydroxytoluene E321
Diethylene glycol
monoethyl ether

Dosage
Volume Weight dog Fipronil (mg) Pyriproxyfen (mg)
0.67 ml 2-10 kg 67 20.1
1.34 ml 10-20 kg 134 40.2
2.68 ml 20-40 kg 268 80.4
4.02 ml 40-60 kg 402 120.6
For dogs > 60 kg, the appropriate combination of pipettes should be used.

Instructions for use
Spot-on use

Method of administration:
Remove the pipette from the blister pack. Hold the pipette upright. Tap against the narrow part of the
pipette to ensure that all contents are in the reservoir of the pipette.
Break off the tip of the spot-on pipette along the break line.
Push the hair aside at the back of the dog's neck until the skin is visible.
Place the tip of the pipette directly against the skin and gently squeeze the pipette several times
to empty it. If necessary, the contents of the pipette can be applied at one or two extra sites
to be administered to prevent the veterinary medicinal product from running off the skin or
applied superficially to the coat, especially in large dogs.

The treatment consists of one pipette, with the possibility of applying it monthly
repeat. For optimal control of flea and tick infestations and their multiplication
fleas, the treatment schedule can be adjusted to the epidemiological situation.
Read the package leaflet before use.
Pay attention to the maximum daily dosage.

Responsible for placing on the market
ALFAMED, 13th street – LID, 06517 Carros Cedex, France